AUTHOR=Ozor Nicholas , Nwakaire Joel , Nyambane Alfred , Muhatiah Wentland , Nwobodo Cynthia TITLE=Enhancing Africa’s agriculture and food systems through responsible and gender inclusive AI innovation: insights from AI4AFS network JOURNAL=Frontiers in Artificial Intelligence VOLUME=Volume 7 - 2024 YEAR=2025 URL=https://www.frontiersin.org/journals/artificial-intelligence/articles/10.3389/frai.2024.1472236 DOI=10.3389/frai.2024.1472236 ISSN=2624-8212 ABSTRACT=The integration of artificial intelligence (AI) technologies into agriculture holds urgent and transformative potential for enhancing food security across Sub-Saharan Africa (SSA), a region acutely impacted by climate change and resource constraints. This paper examines experiences from the Artificial Intelligence for Agriculture and Food Systems (AI4AFS) Innovation Research Network, which provided funding to innovative projects in eight SSA countries. Through a set of case studies, we explore AI-driven solutions for pest and disease detection across crops such as cashew, maize, tomato, and cassava, including a real-time health monitoring tool for Nsukka Yellow pepper. Using participatory design, and key informant interview, robust monitoring and evaluation, and incorporating ethical frameworks, the research prioritizes gender equality, social inclusion, and environmental sustainability in AI development and deployment. Our results demonstrate that responsible AI practices can significantly enhance agricultural productivity while maintaining low carbon footprints. This research offers a unique, localized perspective on AI’s role in addressing SSA’s agricultural challenges, with implications for global food security as demand rises and environmental resources shrink. Key recommendations include establishing robust policy frameworks, strengthening capacity-building efforts, and securing sustainable funding mechanisms to support long-term AI adoption. This work provides the global community, policymakers, and stakeholders with critical insights on establishing ethical, responsible, and inclusive AI practices that can be adapted to similar agricultural contexts worldwide, contributing to sustainable food systems on an international scale.