AUTHOR=Kovačević Andjelka B. , Mason Nigel J. , Ćiprijanović Aleksandra TITLE=Multiscale astrobiology with the Vera C. Rubin Observatory Legacy Survey of Space and Time JOURNAL=Frontiers in Astronomy and Space Sciences VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/astronomy-and-space-sciences/articles/10.3389/fspas.2025.1594485 DOI=10.3389/fspas.2025.1594485 ISSN=2296-987X ABSTRACT=The Vera C. Rubin Observatory’s Legacy Survey of Space and Time (LSST) presents an unprecedented opportunity to advance the search for astrobiologically relevant data across diverse astronomical environments. Through its extensive imaging capabilities, LSST will enhance our inventory of Solar System objects and assess their potential astrobiological conditions. Beyond the Solar System, LSST will survey billions of stars, contributing to the detection of exoplanets, characterizing planetary atmospheres at a zeroth-order level, identifying transient phenomena, and exploring conditions within habitable zones. In this paper, we highlight LSST’s unique contribution to astrobiology, complementing other missions and expanding the search for life beyond Earth in the coming decades.