AUTHOR=Habuchi Satoshi TITLE=Super-Resolution Molecular and Functional Imaging of Nanoscale Architectures in Life and Materials Science JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=Volume 2 - 2014 YEAR=2014 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2014.00020 DOI=10.3389/fbioe.2014.00020 ISSN=2296-4185 ABSTRACT=

Super-resolution (SR) fluorescence microscopy has been revolutionizing the way in which we investigate the structures, dynamics, and functions of a wide range of nanoscale systems. In this review, I describe the current state of various SR fluorescence microscopy techniques along with the latest developments of fluorophores and labeling for the SR microscopy. I discuss the applications of SR microscopy in the fields of life science and materials science with a special emphasis on quantitative molecular imaging and nanoscale functional imaging. These studies open new opportunities for unraveling the physical, chemical, and optical properties of a wide range of nanoscale architectures together with their nanostructures and will enable the development of new (bio-)nanotechnology.