AUTHOR=Taghizadeh Bita , Ghavami Laleh , Derakhshankhah Hossein , Zangene Ehsan , Razmi Mahdieh , Jaymand Mehdi , Zarrintaj Payam , Zarghami Nosratollah , Jaafari Mahmoud Reza , Moallem Shahri Matin , Moghaddasian Adrineh , Tayebi Lobat , Izadi Zhila 

TITLE=Biomaterials in Valvular Heart Diseases

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=Volume 8 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2020.529244

DOI=10.3389/fbioe.2020.529244

ISSN=2296-4185

ABSTRACT=Cardiovascular diseases (CVD) including valvular disease, coronary heart disease, aortic disease, myocardial infarction, cardiac myopathy, heart failure etc., are considered the leading cause of death worldwide. The global commitment to reduce mortality rates related to CVD has enhanced the need for new therapeutic approaches. During the past decade, development of innovative pharmacological and surgical approaches has dramatically improved the quality of life for CVD patients, yet the search for low cost, more effective and less invasive approaches is ongoing. The gold standard approach for CVD management is to replace or repair injured cardiac tissue with natural or synthetic biomaterials. Application of these biomaterials for cardiac regeneration and repair holds a great promise for use in CVD treatment. The focus of the present review is the current use of different types of biomaterials in treatment of valvular heart diseases.