AUTHOR=Faiz Khunza , Lam Fred C. , Chen Jay , Kasper Ekkehard M. , Salehi Fateme 

TITLE=The Emerging Applications of Nanotechnology in Neuroimaging: A Comprehensive Review

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2022.855195

DOI=10.3389/fbioe.2022.855195

ISSN=2296-4185

ABSTRACT=Nanotechnology is an emerging field where engineered nanoparticles (NPs) are used for detection, treatment, and prevention of multiple neurological diseases. Magnetic particle imaging (MPI) is a tracer imaging technique with high spatial and temporal resolution that allows tracking and quantification of NPs. In the field of neuroimaging, MPI has shown promising applications in vascular and oncological imaging, cell tracking and multiple other neurological conditions including neurodegenerative diseases and epilepsy. In this review, we will highlight the applications of MPI in neuroimaging, briefly discuss the limitations in the use of NPs and explore the future implication of this emerging imaging modality.