AUTHOR=Wang Yaqing , Ruan Huajiang , Ruan Yaoqin , Li Qi , Wang Chen , Fang Zhaoxi TITLE=Intelligent blood collection robot: key technologies, clinical applications, and future challenges JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2025.1587114 DOI=10.3389/fbioe.2025.1587114 ISSN=2296-4185 ABSTRACT=Blood collection is one of the key steps in blood testing. The use of intelligent blood collection robots to achieve automated blood collection can effectively reduce the workload of medical staff, improve the efficiency and accuracy of blood collection, and improve the patient experience, and has received extensive attention from academic and industrial circles in recent years. This paper aims to provide a comprehensive introduction to the key technologies, latest research progress, current clinical application status, and future development opportunities and challenges of intelligent blood collection robots. The paper introduces the key technologies that can achieve autonomous blood collection, including blood vessel recognition and positioning technology, mechanical arm design, and puncture control technology. Among them, blood vessel recognition and positioning is one of the key supporting technologies for intelligent blood collection, which can be realized by using technologies such as machine vision, near-infrared imaging, and ultrasound imaging. In addition, the paper also introduces some existing commercial intelligent blood collection robots and their clinical application cases in hospitals. Finally, we analyze the future application prospects and challenges of intelligent blood collection robots.