AUTHOR=Ben Abdallah Ismail , Bouteraa Yassine , Alotaibi Ahmed 

TITLE=AI-driven hybrid rehabilitation: synergizing robotics and electrical stimulation for upper-limb recovery after stroke

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=Volume 13 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2025.1619247

DOI=10.3389/fbioe.2025.1619247

ISSN=2296-4185

ABSTRACT=This study presents an AI-enhanced hybrid rehabilitation system that integrates a dual-arm robotic platform with electromyography (EMG)-guided neuromuscular electrical stimulation (NMES) to support upper-limb motor recovery in stroke survivors. The system features a symmetrical robotic arm with real-time anatomical adaptation for bilateral therapy and incorporates a Support Vector Machine (SVM)-based model for continuous muscle fatigue detection using time-frequency features extracted from EMG signals. A ROS2-based architecture enables real-time signal processing, adaptive control, and remote supervision by clinicians. The system dynamically adjusts stimulation parameters based on fatigue classification results, allowing personalized and responsive therapy. Preliminary clinical validation with three post-stroke patients demonstrated a 44% increase in range of motion, 45% enhancement in active torque, and 36% reduction in passive torque. The SVM model achieved a 95% accuracy in fatigue detection, and initial patient results suggest the feasibility and potential benefits of this intelligent, closed-loop rehabilitation approach.