Frontiers in Bioinformatics | New and Recent Articles https://www.frontiersin.org/journals/bioinformatics RSS Feed for Frontiers in Bioinformatics | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-08-07T22:23:32.96+00:00 60 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1887419 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1887419 <![CDATA[AI-enhanced virtual screening identifies a potent small-molecule modulator of ClC-3 for cervical cancer drug discovery]]> 2026-08-07T00:00:00Z Original Research Chao LiuChongxing Ji https://www.frontiersin.org/articles/10.3389/fbinf.2026.1911554 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1911554 <![CDATA[Integrated analysis of enzymes, mRNAs, and miRNAs provides insight into the regulatory potential of extracellular vesicles in recipient cell glucose metabolism]]> 2026-08-07T00:00:00Z Original Research Namita N. KashyapSharath Mohan BhatPadmanabha Udupa E. G.Kavitha S. ShettigarVinutha R. BhatDinesh Upadhya https://www.frontiersin.org/articles/10.3389/fbinf.2026.1832826 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1832826 <![CDATA[Spatial transcriptomics reveal heterogeneous cell‒cell interactions among brain regions in cuprizone model consistent with multiple sclerosis lesions]]> 2026-08-06T00:00:00Z Original Research Hui-Hsin TsaiSarbottam PiyaJing WangJing ZhuWenxing HuAndrew R. GehrkeShaolong CaoAmanda J. GuiseSu Jing ChanMark SheehanJenhwa ChuZhengyu OuyangMatthew RyalsMichelle LeeWanli WangEdward ZhaoPatrick CullenRavi ChallaEric MarshallWanyong ZengYea Jin Kaeser-WooChris EhrenfelsLuke JandreskiHelen McLaughlinThomas M. CarlileJake GagnonTaylor L. ReynoldsMingyao LiKejie LiBaohong Zhang https://www.frontiersin.org/articles/10.3389/fbinf.2026.1894439 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1894439 <![CDATA[Decoding the hypoxic injury landscape and hypoxic risk model construction in diabetic kidney disease: a multi-omics study]]> 2026-08-05T00:00:00Z Original Research Li JiangChien ChiehHaojun ZhangTingting ZhaoXiai Wu https://www.frontiersin.org/articles/10.3389/fbinf.2026.1827877 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1827877 <![CDATA[SiaRNA: a siamese neural network with bidirectional cross-attention for pairwise siRNA-mRNA efficacy prediction]]> 2026-08-05T00:00:00Z Original Research Vaishnavi SapireddyRajkumar NathiVenkata Harshit MeruvaVarun Raju NannapurajuBhargava Chary BasangariVani Kondaparthi https://www.frontiersin.org/articles/10.3389/fbinf.2026.1883130 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1883130 <![CDATA[MultiCausGRN: directed prior-guided graph attention model for multi-omics gene regulatory network inference]]> 2026-08-04T00:00:00Z Original Research Noor Jamal AlkhateebMamoun Awad https://www.frontiersin.org/articles/10.3389/fbinf.2026.1882476 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1882476 <![CDATA[LNMGAT: a laplacian regularized pseudo-negative mining graph attention network for robust drug–target interaction prediction under multi-scenario cold-start settings]]> 2026-07-31T00:00:00Z Original Research Shuai GuoWeichi LiuJie ZouTao BanGaifang Dong https://www.frontiersin.org/articles/10.3389/fbinf.2026.1821527 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1821527 <![CDATA[Molecular docking and dynamics simulation studies uncover the host–pathogen protein–protein interactions in soybean (Glycine max (L.) Merr.) and Groundnut bud necrosis virus: first report]]> 2026-07-31T00:00:00Z Original Research Rayees Ahmad BhatAyyagari RamlalAmooru HarikaAshutosh SharmaAmbika RajendranIten M. FawzySreeramanan SubramaniamDhandapani RajuS. K. LalSonu KrishankumarShyam S. Kurup https://www.frontiersin.org/articles/10.3389/fbinf.2026.1902380 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1902380 <![CDATA[A linked independent component analysis framework for characterizing site-effect patterns in multi-site structural and functional MRI]]> 2026-07-29T00:00:00Z Original Research Huashuai XuYuge XingWeiya Guo https://www.frontiersin.org/articles/10.3389/fbinf.2026.1846380 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1846380 <![CDATA[Computational design of immunogenic peptide–ligand conjugates for targeted therapy against Nipah virus infection]]> 2026-07-27T00:00:00Z Original Research Sudip Prasad JenaPrateek NayakM. A. AdithyanManoviraj MoreyR. Vihaas TharsiniAbilash Valsala GopalakrishnanKuntal PalSabina Evan Prince https://www.frontiersin.org/articles/10.3389/fbinf.2026.1851023 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1851023 <![CDATA[Instability of LLM text embeddings for unsupervised dimension reduction of tabular data]]> 2026-07-27T00:00:00Z Original Research Jun LiYixuan GouShawn SuMujun XuBrendan Chen https://www.frontiersin.org/articles/10.3389/fbinf.2026.1875897 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1875897 <![CDATA[Functional restoration of conformational (R175H) and contact (R273H) mutant p53 by Bacillus-derived Hydroxymycotrienin A in non-small cell lung cancer: a computational approach]]> 2026-07-24T00:00:00Z Original Research Adeline Celina RufusSidharth Kumar NMagesh RamasamyElavarashi Elangovan https://www.frontiersin.org/articles/10.3389/fbinf.2026.1839606 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1839606 <![CDATA[In silico drug discovery pipelines targeting antibiotic resistance: from genomes to leads]]> 2026-07-24T00:00:00Z Review Rohan GuptaPallavi SinghKarthikeyan RaviMosleh Mohammad AbomughaidSorabh LakhanpalRavi SharmaNaveen KumarNiraj Kumar Jha https://www.frontiersin.org/articles/10.3389/fbinf.2026.1770712 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1770712 <![CDATA[Integrative phosphoproteomics reveals kinase-mediated regulation of OCIAD1 and its roles in mitochondrial quality control]]> 2026-07-23T00:00:00Z Original Research Amal FahmaSuhail SubairFathimathul LubabaAthira Perunelly GopalakrishnanPrathik Basthikoppa ShivamurthyRajesh Raju https://www.frontiersin.org/articles/10.3389/fbinf.2026.1858891 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1858891 <![CDATA[Analysing open-source protein folding models for nanobody binding prediction]]> 2026-07-22T00:00:00Z Original Research Yannick VogtRebekka RoßbergJan HabermannPia KlugeWendan XuMehdi NaouarStefan HirschbergCornelius MiethingJoschka BödeckerMaria KalweitEvelyn UllrichGabriel Kalweit https://www.frontiersin.org/articles/10.3389/fbinf.2026.1858518 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1858518 <![CDATA[Pan-cancer multi-omics analysis of pharmacogenomic alterations]]> 2026-07-22T00:00:00Z Original Research Aisha AlMullaSimerpreet KaurPrachi BalyanSana Al-SaafinManoj Kumar BalyanDinesh VelayuthamPuthen Veettil Jithesh https://www.frontiersin.org/articles/10.3389/fbinf.2026.1877345 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1877345 <![CDATA[Diagnostic accuracy and repeatability of ChatGPT using textual and radiographic data in reversible pulpitis: a retrospective diagnostic study]]> 2026-07-21T00:00:00Z Original Research María Llorente de PedroYolanda FreireNatalia MoneoCristina Andreu-VázquezRoberto EstévezVíctor Díaz-Flores GarcíaAna Suárez https://www.frontiersin.org/articles/10.3389/fbinf.2026.1844071 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1844071 <![CDATA[Clinically interpretable deep learning for breast cancer missense variant pathogenicity prediction]]> 2026-07-21T00:00:00Z Original Research Rahaf M. AhmadNoura AlDhaheriMohd Saberi MohamadBassam R. Ali https://www.frontiersin.org/articles/10.3389/fbinf.2026.1876523 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1876523 <![CDATA[Radiation-induced network rewiring in cancer: systems-level insights into environmental radioactivity and precision oncology]]> 2026-07-20T00:00:00Z Review Marckasagayam PriyadharshiniSaravanan Sekaran https://www.frontiersin.org/articles/10.3389/fbinf.2026.1870490 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1870490 <![CDATA[Network pharmacology and molecular modelling analysis of Arctium lappa phytochemicals in valproic acid–induced hepatotoxicity and pancreatitis]]> 2026-07-20T00:00:00Z Original Research Mukul ShyamSabina Evan Prince