Frontiers in Bioinformatics | Computational BioImaging section | New and Recent Articles https://www.frontiersin.org/journals/bioinformatics/sections/computational-bioimaging RSS Feed for Computational BioImaging section in the Frontiers in Bioinformatics journal | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-05-10T23:12:07.796+00:00 60 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1733655 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1733655 <![CDATA[Weak-to-strong generalization enables fully automated training of multi-head mask-RCNN model for segmenting densely overlapping cell nuclei in multiplex whole-slice brain images]]> 2026-05-11T00:00:00Z Methods Lin BaiXiaoyang LiLiqiang HuangQuynh NguyenHien Van NguyenSaurabh PrasadDragan MaricJohn RedellPramod DashBadrinath Roysam https://www.frontiersin.org/articles/10.3389/fbinf.2026.1713736 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1713736 <![CDATA[Automated segmentation of hepatic vessels and lobules in whole-slide images using U-net models]]> 2026-04-30T00:00:00Z Original Research Mehul BafnaMatthias KönigSylvia SaalfeldVladimira MoulisovaVaclav LiskaUta DahmenMohamed Albadry https://www.frontiersin.org/articles/10.3389/fbinf.2026.1821804 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1821804 <![CDATA[DEP-track: a motion-aware framework for large-scale cell tracking and crossover frequency estimation in dielectrophoresis]]> 2026-04-23T00:00:00Z Original Research Sena LeeSeungyeop ChoiYerin LeeHyunmin BaeJunghun HanYoon Suk KimSang Woo LeeSejung Yang https://www.frontiersin.org/articles/10.3389/fbinf.2026.1748364 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1748364 <![CDATA[An automated cell-tracking pipeline for the analysis of neutrophil dynamics]]> 2026-04-21T00:00:00Z Original Research Chen LiWilson W. C. YiuWanbin HuHerman P. SpainkLu CaoFons J. Verbeek https://www.frontiersin.org/articles/10.3389/fbinf.2026.1746714 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1746714 <![CDATA[SpatialFinder: a human-in-the-loop vision-language framework for prioritizing high-value regions in spatial transcriptomics]]> 2026-04-15T00:00:00Z Original Research Jonathan XuMichelle JiangShunsuke KogaNancy ZhangZhi Huang https://www.frontiersin.org/articles/10.3389/fbinf.2026.1657030 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1657030 <![CDATA[Resolving heterogeneity in Lymph Node Stromal Cells using high-dimensional analysis of non-optimized flow cytometry data]]> 2026-04-14T00:00:00Z Methods Mikala E. HeonEduardo Rosa-Molinar https://www.frontiersin.org/articles/10.3389/fbinf.2026.1771574 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1771574 <![CDATA[Automated deep learning based detection of cellular deposits on clinically used ECMO membrane lungs]]> 2026-04-01T00:00:00Z Original Research Daniel PointnerMichael KranzMaria Stella WagnerMoritz HausKarla LehleLars Krenkel https://www.frontiersin.org/articles/10.3389/fbinf.2026.1765143 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1765143 <![CDATA[A toolkit for generating virtual brightfield images of histological and immunohistochemical stains from multiplexed data with AI-based channel selection and image enhancement]]> 2026-03-09T00:00:00Z Original Research Tristan WhitmarshMohammad Al Sa’dEduardo González SolaresAlireza MolaeinezhadMelis O. IrfanClaire MulveyMarta Paez-RibesAtefeh FatemWei CopeKui HuaGregory HannonDario BressanNicholas Walton https://www.frontiersin.org/articles/10.3389/fbinf.2026.1768786 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1768786 <![CDATA[ZR2ViM: a recursive vision Mamba model for boundary-preserving medical image segmentation]]> 2026-03-04T00:00:00Z Original Research Caijian HuaCaorong XiangLiuying LiXia Zhou https://www.frontiersin.org/articles/10.3389/fbinf.2026.1738132 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1738132 <![CDATA[SimpleKANSleepNet: a Kolmogorov–Arnold network based sleep stage classification method]]> 2026-02-18T00:00:00Z Original Research Xiaopeng JiLei WangYong Zhou https://www.frontiersin.org/articles/10.3389/fbinf.2026.1711797 https://www.frontiersin.org/articles/10.3389/fbinf.2026.1711797 <![CDATA[Label-free TIMING: an efficient, reliable and scalable AI workflow for automated profiling of cell-cell interaction behaviors in nanowell arrays]]> 2026-02-12T00:00:00Z Methods Anuj S. TodkarShyam Reddy KothaLin BaiSaikiran MandulaHannah B. WilsonDaniel D. MeyerRebecca BerdeauxBadrinath RoysamNavin Varadarajan https://www.frontiersin.org/articles/10.3389/fbinf.2025.1677527 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1677527 <![CDATA[Deep learning software and revised 2D model to segment bone in micro-CT scans]]> 2026-01-21T00:00:00Z Technology and Code Andrew H. LeeGanesh TalluriManan DamaniBrandon Vera CovarrubiasHelena HannaJeremy ChavezJulian M. MooreJacob BaradarianMichael MolgaardBeau NielsonKalah WaldenThomas L. BroderickLayla Al-Nakkash https://www.frontiersin.org/articles/10.3389/fbinf.2025.1725145 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1725145 <![CDATA[Stain-free artificial intelligence-assisted light microscopy for the identification of leukocyte morphology change in presence of bacteria]]> 2026-01-06T00:00:00Z Original Research Alexander HuntHolger SchulzeKay SamuelRobert B. FisherTill T. Bachmann https://www.frontiersin.org/articles/10.3389/fbinf.2025.1645520 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1645520 <![CDATA[Segmentation and modeling of large-scale microvascular networks: a survey]]> 2025-10-31T00:00:00Z Review Helya GoharbavangArtem T. AshitkovAthira PillaiJoshua D. WytheGuoning ChenDavid Mayerich https://www.frontiersin.org/articles/10.3389/fbinf.2025.1693343 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1693343 <![CDATA[The importance of democratized resources in early-career training for bioimage analysts and bioimaging scientists]]> 2025-10-30T00:00:00Z Perspective Genevieve LapradeQuinn LeeKristin L. GallikMichael NelsonNatalie WooCelina Terán RamírezAlexis Ricardo Becerril CuevasKevin W. EliceiriCorinne Esquibel https://www.frontiersin.org/articles/10.3389/fbinf.2025.1609004 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1609004 <![CDATA[Analysis of breast region segmentation in thermal images using U-Net deep neural network variants]]> 2025-10-10T00:00:00Z Original Research Rafhanah Shazwani RosliMohamed Hadi HabaebiMd Rafiqul IslamMohammed Abdulla Salim Al Hussaini https://www.frontiersin.org/articles/10.3389/fbinf.2025.1619790 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1619790 <![CDATA[An image analysis pipeline to quantify the spatial distribution of cell markers in stroma-rich tumors]]> 2025-09-05T00:00:00Z Technology and Code Antoine A. RuzetteNina KozlovaKayla A. CruzTaru MuranenSimon F. Nørrelykke https://www.frontiersin.org/articles/10.3389/fbinf.2025.1567219 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1567219 <![CDATA[Novel deep learning for multi-class classification of Alzheimer’s in disability using MRI datasets]]> 2025-08-20T00:00:00Z Original Research Sumaiya Binte ShahidMaleeha KaikausMd. Hasanul KabirMohammad Abu YousufA. K. M. AzadA. S. Al-MoisheerNaif AlotaibiSalem A. AlyamiTouhid BhuiyanMohammad Ali Moni https://www.frontiersin.org/articles/10.3389/fbinf.2025.1628724 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1628724 <![CDATA[Stain-free artificial intelligence-assisted light microscopy for the identification of blood cells in microfluidic flow]]> 2025-08-14T00:00:00Z Original Research Alexander HuntHolger SchulzeKay SamuelRobert B. FisherTill T. Bachmann https://www.frontiersin.org/articles/10.3389/fbinf.2025.1613866 https://www.frontiersin.org/articles/10.3389/fbinf.2025.1613866 <![CDATA[Trail-blazing and keeping pace: building, retaining and expanding image analysis expertise]]> 2025-05-30T00:00:00Z Perspective David KirchenbuechlerMariana De NizConstadina Arvanitis