Frontiers in Biophysics | New and Recent Articles https://www.frontiersin.org/journals/biophysics RSS Feed for Frontiers in Biophysics | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-08-12T17:58:22.170+00:00 60 https://www.frontiersin.org/articles/10.3389/frbis.2026.1925801 https://www.frontiersin.org/articles/10.3389/frbis.2026.1925801 <![CDATA[Silent Kv subunits as major players in cell membrane excitability]]> 2026-08-12T00:00:00Z Review Mohammed AlshemeryMert BeyazyildirimJoao L. Carvalho-de-Souza https://www.frontiersin.org/articles/10.3389/frbis.2026.1870174 https://www.frontiersin.org/articles/10.3389/frbis.2026.1870174 <![CDATA[Probing peptide-mediated membrane pore formation by fluorescence, infrared spectroscopy, and atomic force microscopy]]> 2026-08-06T00:00:00Z Mini Review Suren A. TatulianMunira Haque https://www.frontiersin.org/articles/10.3389/frbis.2026.1781425 https://www.frontiersin.org/articles/10.3389/frbis.2026.1781425 <![CDATA[Targeting cancer matrix mechanics: fibronectin fiber relaxation correlates with ADAM8 expression in PDAC and is amenable to in vitro modulation]]> 2026-08-06T00:00:00Z Original Research Konstantin M. P. WolfLea S. OttenwaldMartin WartenbergMamta ChabriaViola Vogel https://www.frontiersin.org/articles/10.3389/frbis.2026.1926644 https://www.frontiersin.org/articles/10.3389/frbis.2026.1926644 <![CDATA[Editorial: Structural and functional roles of membrane transport proteins in cellular physiology]]> 2026-07-24T00:00:00Z Editorial Olga Vinogradova https://www.frontiersin.org/articles/10.3389/frbis.2026.1769000 https://www.frontiersin.org/articles/10.3389/frbis.2026.1769000 <![CDATA[From scattering curves to structural descriptors: interpretable machine learning maps SAXS/WAXS signals to RNA structural details in defined RNA motifs]]> 2026-07-14T00:00:00Z Original Research Weiwei HeSerdal Kirmizialtin https://www.frontiersin.org/articles/10.3389/frbis.2026.1880887 https://www.frontiersin.org/articles/10.3389/frbis.2026.1880887 <![CDATA[Intrinsically disordered regions as drivers of protein aggregation: mechanisms, phase separation, and emerging predictive frameworks]]> 2026-07-10T00:00:00Z Mini Review Rahul KaushikSuyong Re https://www.frontiersin.org/articles/10.3389/frbis.2026.1839006 https://www.frontiersin.org/articles/10.3389/frbis.2026.1839006 <![CDATA[Chromatic discrimination in protocells toward proto vision and intelligence]]> 2026-07-08T00:00:00Z Original Research Panagiotis MougkogiannisAndrew Adamatzky https://www.frontiersin.org/articles/10.3389/frbis.2026.1677942 https://www.frontiersin.org/articles/10.3389/frbis.2026.1677942 <![CDATA[Threshold transitions of 15N fluxes reveal state-dependent root conductance and flux partitioning within steady-state nitrate isotherms]]> 2026-06-08T00:00:00Z Hypothesis and Theory Erwan Le DeunffPhilippe Malagoli https://www.frontiersin.org/articles/10.3389/frbis.2026.1860065 https://www.frontiersin.org/articles/10.3389/frbis.2026.1860065 <![CDATA[Biomolecular condensation meets membrane biophysics: from interfacial physical principles to emerging therapeutic opportunities]]> 2026-06-01T00:00:00Z Mini Review Agustín MangiarottiErnesto E. AmbroggioM. Soledad Celej https://www.frontiersin.org/articles/10.3389/frbis.2026.1808825 https://www.frontiersin.org/articles/10.3389/frbis.2026.1808825 <![CDATA[Linker peptide acts as an external mechanical clamp in a designed polyprotein]]> 2026-05-04T00:00:00Z Original Research Yanwei WangBin ZhengPeng Zheng https://www.frontiersin.org/articles/10.3389/frbis.2026.1773451 https://www.frontiersin.org/articles/10.3389/frbis.2026.1773451 <![CDATA[Novel therapeutic approaches targeting biomechanical pathway alterations in bone diseases]]> 2026-04-01T00:00:00Z Review Malkiet KaurManju Nagpal https://www.frontiersin.org/articles/10.3389/frbis.2026.1795884 https://www.frontiersin.org/articles/10.3389/frbis.2026.1795884 <![CDATA[From the classical colloidal theory to biomolecular condensation: implications in health and disease]]> 2026-03-25T00:00:00Z Mini Review Noelia A. MelianAldana GomezMilagros B. AbatePamela L. ToledoMario R. ErmácoraDiego S. Vazquez https://www.frontiersin.org/articles/10.3389/frbis.2026.1804302 https://www.frontiersin.org/articles/10.3389/frbis.2026.1804302 <![CDATA[IDRs in Cross-Membrane Transport: Regulation of Ion Channels and Transporters, Mechanistic Studies Made Possible by NMR and Computational Methods]]> 2026-03-09T00:00:00Z Review Olga Vinogradova https://www.frontiersin.org/articles/10.3389/frbis.2025.1710099 https://www.frontiersin.org/articles/10.3389/frbis.2025.1710099 <![CDATA[Functional study of a novel SCN4A variant c.611C>T identified in a Japanese patient with myasthenia]]> 2026-01-08T00:00:00Z Original Research Natsuki KiraKosuke YoshidaSatoe TakahashiAyami YamanakaTakashi KimuraKazuaki HommaMasanori P. TakahashiTomoya Kubota T) located at the 3′ end of exon 4 in SCN4A. The analysis of the proband’s SCN4A mRNA showed that this variant causes an alanine-to-valine missense change at the amino acid position of 204 (p.A204V, 39%) and a disruption of the splicing of exons 4 and 5 leading to the production of truncated Nav1.4 variant protein (p.A204Vfs*94, 4%). We anticipated that the p.A204V missense change would impair Nav1.4 function; however, the ion channel activity and membrane targeting of p.A204V Nav1.4 were found to be wild-type (WT)-like. We also examined the cytotoxicities of the p.A204V and p.A204Vfs*94 variants; however, the cell lines heterologously overexpressing these Nav1.4 variant proteins did not induce cell death any more than the WT control. Although the loss or gain of anomalous ion channel function that is commonly suspected in channelopathies was ruled out in the present case, the precise mechanism of the pathogenic role of c.611C>T SCN4A remains to be elucidated.]]> https://www.frontiersin.org/articles/10.3389/frbis.2025.1693360 https://www.frontiersin.org/articles/10.3389/frbis.2025.1693360 <![CDATA[A blurry view of fuzzy objects: on the roles of low-resolution structural techniques in discovery and early characterization of intrinsically disordered proteins]]> 2025-12-03T00:00:00Z Review Vladimir N. Uversky https://www.frontiersin.org/articles/10.3389/frbis.2025.1693508 https://www.frontiersin.org/articles/10.3389/frbis.2025.1693508 <![CDATA[Vesicular and plasma membrane glutamate transporters]]> 2025-10-30T00:00:00Z Review Bart BorghansNatalia DmitrievaAleksandr NikiforovChristoph Fahlke https://www.frontiersin.org/articles/10.3389/frbis.2025.1681011 https://www.frontiersin.org/articles/10.3389/frbis.2025.1681011 <![CDATA[Proton channel Hv1 modulates microglial responses to neurological disorders]]> 2025-10-08T00:00:00Z Mini Review Maite StratmannCaterina GagliardiMelania Capasso https://www.frontiersin.org/articles/10.3389/frbis.2025.1652466 https://www.frontiersin.org/articles/10.3389/frbis.2025.1652466 <![CDATA[Identification of voltage-gated calcium currents in Helix (Cornu) serotonergic neurons, subcellular localization, and role in calcium dynamics and cellular firing of CaV2.1 and CaV2.2 subtypes]]> 2025-10-02T00:00:00Z Original Research María Laura Ríos-ReyesSilvia Calvo-CoreaOscar Brenes https://www.frontiersin.org/articles/10.3389/frbis.2025.1648934 https://www.frontiersin.org/articles/10.3389/frbis.2025.1648934 <![CDATA[From biophysics to cellular function: neural TELCs-membrane-anions capacitor transmembrane potential]]> 2025-09-18T00:00:00Z Review James Weifu Lee https://www.frontiersin.org/articles/10.3389/frbis.2025.1623880 https://www.frontiersin.org/articles/10.3389/frbis.2025.1623880 <![CDATA[Nanotribology of viruses reveals their adhesion strength and modality of motion on surfaces]]> 2025-08-07T00:00:00Z Original Research Charles AultClaudia SimonIrina B. TsvetkovaPedro J. De PabloBogdan Dragnea