AUTHOR=Voigtländer Lisa , Seiffert Moritz 

TITLE=Expanding TAVI to Low and Intermediate Risk Patients

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 5 - 2018

YEAR=2018

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2018.00092

DOI=10.3389/fcvm.2018.00092

ISSN=2297-055X

ABSTRACT=TAVI has become the standard treatment in patients at increased surgical risk and is increasingly being performed in patients at intermediate to low surgical risk. While non-inferiority has been demonstrated in intermediate risk patients, several challenges – particularly with regard to valve durability – need to be addressed before expansion to lower risk and younger patients can be recommended on a broad basis. Current trends, trials results, and remaining challenges are summarized and discussed in the light of updated treatment guidelines.