AUTHOR=Ono Masafumi , Kawashima Hideyuki , Hara Hironori , Gao Chao , Wang Rutao , Kogame Norihiro , Takahashi Kuniaki , Chichareon Ply , Modolo Rodrigo , Tomaniak Mariusz , Wykrzykowska Joanna J. , Piek Jan J. , Mori Isao , Courtney Brian K. , Wijns William , Sharif Faisal , Bourantas Christos , Onuma Yoshinobu , Serruys Patrick W. 

TITLE=Advances in IVUS/OCT and Future Clinical Perspective of Novel Hybrid Catheter System in Coronary Imaging

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 7 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2020.00119

DOI=10.3389/fcvm.2020.00119

ISSN=2297-055X

ABSTRACT=Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have been developed and improved as both diagnostic and guidance tools for interventional procedures over the past three decades. IVUS has a resolution of 100 µm with a high tissue penetration and capability of assessing the entire structure of a coronary artery including the external elastic membrane, whereas OCT has a higher resolution of 10-20 µm to assess endoluminal structures with a limited tissue penetration compared to IVUS. Recently, two companies, CONAVI and TERUMO, integrated IVUS and OCT into a single catheter system. With their inherent strength and limitations, the combined IVUS and OCT probes are complementary and work synergistically to enable a comprehensive depiction of coronary artery. In this review we summarize the performance of the two intracoronary imaging modalities - IVUS and OCT, and discuss the expected potential of the novel hybrid IVUS-OCT catheter system in the clinical field.