AUTHOR=Li Yi-ming , Tsauo Jia-yu , Jia Kai-yu , Liao Yan-biao , Xia Fan , Zhao Zheng-gang , Chen Mao , Peng Yong TITLE=Transcatheter and Surgical Aortic Valve Replacement in Patients With Previous Cardiac Surgery: A Meta-Analysis JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 7 - 2020 YEAR=2021 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2020.612155 DOI=10.3389/fcvm.2020.612155 ISSN=2297-055X ABSTRACT=Background: Many patients who have aortic stenosis and are transcatheter aortic valve replacement (TAVR) candidates have underwent prior cardiac surgery (PCS). The aim of this study was to provide a robust summary comparison between patents with PCS who underwent TAVR versus surgical aortic valve replacement (SAVR). Methods: We conducted a systematic review and meta-analysis of all published articles on PubMed/Medline, Ovid, EMBASE and Scopus from 2002 to 2019. Results: Total of 13 studies were finally included, yielding a total of 23,148 participants. There was no statistical difference with 30-day (odds ratio (OR): 1.02(0.86-1.21)) or 1-year mortality (OR: 1.18(0.86-1.61)) between the two groups. Subgroup analysis revealed that high-risk patients who underwent TAVR with the transapical approach were associated with increased risk of mortality (OR: 1.45(1.00-2.11)). However, those who underwent TAVR with endovascular approach had a comparable outcome with SAVR. Conclusions: Primary outcomes after endovascular TAVR was similar to those with SAVR and superior to transapical TAVR treatment group in patients with PCS.