AUTHOR=Lin Xiaoxiao , Wu Guomin , Gao Beibei , Wang Shuai , Huang Jinyu 

TITLE=Bibliometric and visual analysis of coronary microvascular dysfunction

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1021346

DOI=10.3389/fcvm.2022.1021346

ISSN=2297-055X

ABSTRACT=Background: Coronary microvascular dysfunction (CMD) may play an important role in different cardiovascular diseases including HFpEF, obstructive and non-obstructive CAD. To date, there was no a bibliometric
analysis to summarize this field. We aimed to conduct a bibliometric analysis for CMD to determine the current status and frontiers in this field.
Methods: Publications about CMD were from the Web of Science Core Collection database (WOSCC). The WoSCC literature analysis wire and VOSviewer 1.6.16 were used to conduct the analysis.
Results: A total of 785 publications containing 206 reviews and 579 articles were included. The leading authors were Iacopo Olivotto, Paolo G Camici and Carl J Pepine. The most productive institutions were the University of Florence, the Cedars Sinai Medical Center, and Harvard University. The most productive countries were USA, Italy, and England. 237 journals contribute to this field, and the leading journals were the International Journal of Cardiology, European Heart Journal and the JACC. From 2012 to 2021, the top three highest cited articles were all about the association between HFpEF and CMD. The important keywords of this field were heart failure, hypertrophic cardiomyopathy, chest pain, women, coronary flow reserve (CFR), endothelial dysfunction and prognostic value. 
Conclusions: The studies about CMD were relatively limited, and the prominent contribution was from the USA, Italy and England. More studies are needed and the publications from other countries should be improved. The main research hotspots in the CMD field were CMD in patients with HFpEF, sex differences, and the diagnosis and treatment of CMD. It should be paid attention to CMD in patients with HFpEF, and untangling the association between CMD and HFpEF may be helpful to the development of physiology-stratified treatment for patients with CMD and HFpEF.