AUTHOR=Siagian Sisca Natalia , Oetama Susandy , Pohan Fathy Zuandi , Mendel Brian , Lelya Olfi , Sakti Damba Dwisepto Aulia , Kurniawati Yovi TITLE=Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1022183 DOI=10.3389/fcvm.2022.1022183 ISSN=2297-055X ABSTRACT=Background: Patients with congenital heart disease (CHD) are thought to be especially vulnerable to COVID-19 complications. In this study, we would like to assess clinical characteristics and outcomes in patients with CHD affected by COVID-19. Method: A single-center, observational study was conducted in National Cardiovascular Center Harapan Kita (NCCHK). This study included patients with CHD who were hospitalized for COVID-19. The extracted data were baseline characteristics, clinical findings, supportive examination findings, complications, outcomes, and length of stay of the patients. The data were then analyzed using SPSS 26.0 software. Result: Twenty-six patients with CHD and COVID-19 infection were included in our study. There were 24 resolved cases and 2 deaths, four patients experienced complications such as renal insufficiency (1), sepsis (2), and multiorgan failure (1). The median length of stay was 13 days. The most common symptoms experienced by the patients were breathlessness (65.4%), cough (57.7%), and fever (42.3%). Conclusion: We observed a relatively mild COVID-19 clinical course despite prior research showing that patients with cardiovascular comorbidities, such as CHD, have a higher case-fatality rate. This could be because of the smaller sample size, non-standardized diagnosis, severity, treatment, and age group.