AUTHOR=Chen Mingxian , Wang Zhuo , Wang Songyun , Liu Zhenjiang , Li Xuping , Yang Hui , Hu Lin , Wu Zhihong , Li Qiming , Zhou Shenghua TITLE=Electrophysiological characteristics of right- and left-sided Mahaim accessory pathways: A single-center experience in China JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1052465 DOI=10.3389/fcvm.2022.1052465 ISSN=2297-055X ABSTRACT=Background: Mahaim accessory pathway (MAP) are rare accessory pathways (AP) with specific properties. They mostly locate in right side of the heart, but rarely exist in left side. Objectives: The present study aims to analyze the clinical and electrophysiological characteristics of both-sided MFs. Methods: A total of 2249 patients with AP from our center were enrolled between January 1, 2011 and March 27, 2022. 17 patients were diagnosed as MAPs (right-sided n=13, left-side n=4) according to the Mahaim fibers properties during the electrophysiological study (EPS). Results: Mahaim-type Aps constitute 0.75% of all APs. Out of 1553 patients with left-sided APs, 4 patients (0.26%) were diagnosed as Mahaim fiber-mediated tachycardia. Out of 696 patients with right-sided APs, 13 patients (1.9%) were diagnosed as Mahaim fiber. Most Mahaim fibers were located at the free wall of tricuspid and mitral annulus. 7 right-sided patients were atriofasicular MAPs. 6 right-sided patients and all of the left-sided patients were atrioventricular MAPs. M potential only was detected in long length MAPs. Coexistence with other SVTs were also observed both in patients with right-sided and left-sided MAPs. All the patients underwent radiofrequency ablation successfully. Only one patient had tachycardia recurrence during follow-up. Conclusion: Although MAPs are commonly located at tricuspid annulus, left-sided are not impossible. M potential contributes to improvement of the successful ablation.