AUTHOR=Xiu Wen-Juan , Yang Hai-Tao , Zheng Ying-Ying , Wu Ting-Ting , Hou Xian-Geng , Jiang Zhi-Hui , Yang Yi , Ma Yi-Tong , Xie Xiang 

TITLE=ALB-dNLR Score Predicts Mortality in Coronary Artery Disease Patients After Percutaneous Coronary Intervention

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.709868

DOI=10.3389/fcvm.2022.709868

ISSN=2297-055X

ABSTRACT=Background: The influence of the albumin/derived neutrophil and lymphocyte ratio (ALB-dNLR) on outcomes of coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI) is not known. Here, we aimed to determine the association between ALB-dNLR score and post-PCI CAD patient outcomes. 
Methods: Patients from the First Affiliated Hospital of Xinjiang Medical University were enrolled from January 2008 until December 2016., The 5826 patients were divided into three groups by their ALB-dNLR scores (0 point, n=1826; 1 point, n=3697;2 points, n=261). Mortality after PCI (all-cause [ACM) and cardiac [CM) was taken as the primary endpoint. The prognostic value of ALB-dNLR score was determined with the Cox-proportional hazard model after adjustment for covariates.
Results: Both ACM and CM rates differed among the three groups (P= 0.005 and P= 0.049, respectively) Multivariate Cox analysis showed that ALB-dNLR independently predicted both ACM (1 point vs. 0 point, HR=1.492, [95%CI: 1.131-1.968], P=0.005; 2 point vs. 0 point HR=1.762, [95%CI: 1.020-3.043], P=0.042) and CM (1 point vs. 0 point, HR=1.323, [95%CI: 0.978-1.789], P=0.069; 2 point vs. 0 point HR=1.900, [95%CI: 1.076-3.357], P=0.027).
Conclusion: The ALB-dNLR score predicts mortality in CAD patients after PCI.