AUTHOR=Gabarre Paul , Ruiz Pablo , Chenevier-Gobeaux Camille , Charpentier Etienne , Soulat-Dufour Laurie , Cohen Ariel , Monnier-Cholley Laurence , Chemali Lotfi , François Hélène , Kerneis Mathieu , Lefèvre Guillaume , Boissan Mathieu 

TITLE=Inverted Takotsubo Syndrome With HELLP Syndrome: A Case Report

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.832098

DOI=10.3389/fcvm.2022.832098

ISSN=2297-055X

ABSTRACT=Background: Takotsubo syndrome is a non-ischemic cardiomyopathy involving sudden, transient apical ballooning of the heart muscle that may be triggered by emotional stress and some non-cardiac conditions. Its diagnosis is based on clinical presentation, electrocardiogram, imaging and biomarkers. 
Case summary: Here, we present a novel case report of a patient presenting very soon after childbirth with an unusual form of Takotsubo cardiomyopathy accompanied by HELLP syndrome. Whereas the overall kinetics of changes in troponin I, troponin T and NT-proBNP levels were similar, the amount of troponin I was much greater and its rate of increase was much faster than that of troponin T. NT-proBNP levels peaked at the same time as the troponins. 
Discussion: Our findings indicate that assaying circulating cardiac markers, especially troponin I and NT-proBNP, may be most useful for diagnosis of Takotsubo cardiomyopathy. They illustrate the importance of biomarkers in the diagnosis of this disease.