AUTHOR=Sayed Ahmed Ibrahim TITLE=Case report: Spontaneous coronary artery rupture presenting with acute coronary syndrome: A rare diagnosis of common disease JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.922180 DOI=10.3389/fcvm.2022.922180 ISSN=2297-055X ABSTRACT=Acute coronary syndrome (ACS), myocardial infarction, and sudden death have all been linked to spontaneous coronary artery rapture (SCAR). Patients primarily afflicted by SCAR are those with or without few cardiovascular risk factors, notably men, implying a mechanism distinct from the more prevalent atherosclerosis. Both medical and interventional treatment should take into account the diverse causes of ACS as well as the patient's clinical stability. We herein report an unusual case of a 33 years old male who presented with acute chest pain to emergency department. His physical exam was within normal. The electrocardiogram showed non-specific ST segment changes in anterior leads, and the echocardiogram revealed mild anterior wall hypokinesia with no evidence of pericardial effusion. He underwent Coronary angiography which revealed contained rupture in anterior coronary artery. The patient underwent uneventful lifesaving coronary artery bypass grafting. It concluded that, though rare, SCAR should be considered as a differential diagnosis in patients with acute coronary syndrome, even in the absence of pericardial effusion in adult patients of all ages