AUTHOR=Tong Jishuang , Li Xinggui , Liang Xiaoyue , Tang Fang , Ren Yanling , Hao Guang , Peng Xin , Luo Sunqing , Feng Ye , Huang Daochao , Zhao Li , Liang Xiaohua 

TITLE=The relationship of remnant cholesterol and abdominal obesity in children: A cross-sectional study

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.929560

DOI=10.3389/fcvm.2022.929560

ISSN=2297-055X

ABSTRACT=Background 
Previous studies have found that remnant cholesterol (RC) is a risk factor for cardiovascular diseases and childhood obesity is associated with cardiometabolic diseases. This study aims to explore the relationship between remnant cholesterol and abdominal obesity in children. 
Methods
A total of 5959 children, aged 6~12 years old, were selected from a cross-sectional study in urban-rural areas of Chongqing, China. RC was calculated by total cholesterol - high-density lipoprotein cholesterol - low-density lipoprotein cholesterol, and was divided into four groups by quartiles (Q1–Q4).
Results
Compared to children with the lowest RC (Q1), children with higher RC had significantly higher odds of abdominal obesity (Q2: OR=1.450, 95%CI: 1.131~1.859, P<0.05; Q3: OR=2.127, 95%CI: 1.632~2.772, P<0.001; Q4: OR=2.386, 95%CI: 1.819~3.130, P<0.001). In the stratified analyses by urban-rural areas, the odds ratios were greater in rural areas (Q2: OR=2.228, 95%CI: 1.572~3.160, P<0.001; Q3: OR=3.668, 95%CI: 2.191~6.140, P<0.001; Q4: OR=6.490, 95%CI: 2.271 ~18.551, P<0.001) than in urban areas (Q2: OR=1.644, 95%CI: 1.192~2.266, P<0.05; Q3: OR=2.266, 95%CI: 1.667~3.082, P<0.001; Q4: OR=2.711, 95%CI: 2.005~3.665, P<0.001).
Conclusions
Our study found that RC was positively correlated with abdominal obesity in children, and this association was higher for children living in rural areas.