AUTHOR=Wang Ya , Li Dandan , Jia Zijun , Hui Jiaqi , Xin Qiqi , Zhou Qingbing , Cong Weihong , Xu Fengqin 

TITLE=A Bibliometric Analysis of Research on the Links Between Gut Microbiota and Atherosclerosis

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.941607

DOI=10.3389/fcvm.2022.941607

ISSN=2297-055X

ABSTRACT=Background: Emerging evidence has linked gut microbiota (GM) and its related metabolites to atherosclerosis (AS). This study aimed to analyze the evolution of GM in AS in the past decades, and provide valuable insights in this field. 
Methods: Web of Science Core Collection (WoSCC) was applied to retrieve the publications related to GM in AS from their inception until December 2, 2021, and the data was analyzed in Microsoft Excel, Scimago Graphica, CiteSpace, and VOSviewer. 
Results: In total, 560 documents were extracted from the WoSCC databases. The publications have shown rapid growth since 2008. China and Cleveland Clin were the most prolific country and institution, respectively. The journal with the most publications is Nutrients, and Nature was the most co-cited journal. Among 3,556 related authors, Hazen, Stanley L., Tang, W. H. Wilson, and Wang, Zeneng were the top three contributing authors in this field. Aside from “gut microbiota”, “atherosclerosis”, the terms "TMAO", "metabolite", "obesity", and "phosphatidylcholine" were frequently occurred in the abstract and title of articles. Burst detection of keywords indicated that “acid” and “bile acid” were hot topics in recent years. According to the co-citation analysis of references, the research focus in this area has changed over time, and recent researches focus on choline, hypertension, butyrate, and berberine.
Conclusion: Our study showed that the researches of GM in AS have been flourishing, and the content themes were constantly deepened. Human GM is critical