AUTHOR=Tang Jianjun , Wu Zhihong , He Jia , Hu Qingdan , Yao Jun , Hu Lin , Zhou Shenghua , Chen Mingxian TITLE=Case Report: A Huge Calabash Heart: A Rare Case of Supracardiac Total Anomalous Pulmonary Venous Return JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.942808 DOI=10.3389/fcvm.2022.942808 ISSN=2297-055X ABSTRACT=A 46-year-old female was admitted to cardiovascular department because of a 3-month history of palpitations and exertional dyspnea. She had a history of a successful pregnancy at very young age. Chest radiograph presented a classical ‘calabash’ configuration. Echocardiogram discovered a large atrial septal defect with a suspected pulmonary vein abnormality. Cardiac CT revealed supracardiac total anomalous pulmonary venous return, whereby all the pulmonary veins drain into vertical vein and finally to the superior vena cava. Cardiac catheterisation was consistent with anomalous pulmonary venous drainage without pulmonary hypertension. Finally, she underwent a successful surgical repair and appeared asymptomatic before her discharge.