AUTHOR=Yuan Yuxing , Pan Bo , Liang Xiaohua , Lv Tiewei , Tian Jie 

TITLE=Health-related quality of life in children with congenital heart disease following interventional closure versus minimally invasive closure

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.974720

DOI=10.3389/fcvm.2022.974720

ISSN=2297-055X

ABSTRACT=OBJECTIVE: To evaluate and compare the health-related quality of life (HRQL) of children with simple atrial septal defect (ASD) or ventricular septal defect (VSD) who underwent either Minimally invasive closure (MIC) or Interventional closure (IC) therapy.
Methods: This observational and comparative study was conducted at the Children’s Hospital of Chongqing Medical University. Children aged 2 to 4.5 years old who underwent closure treatment for simple ASD or VSD were included from February 2021 to September 2021. All children had their HRQL assessed using the PedsQLTM3.0 Cardiac Module preoperatively and subsequent follow-ups (3 and 6 months).
Results: A total of 199 children’s data were collected both from IC group (n=116) and MIC group (n=83).  Demographics, baseline clinical characteristics and pre-operative data were generally balanced between the two groups. The duration of anesthesia (45 mins vs. 109 mins), surgery (25 mins vs. 48 mins), and length of postoperative hospital stay (4.32 days vs. 6.87 days) in the IC group were significantly lower compared to the MIC group (P < 0.001). The incidence of postoperative pneumonia in the MIC group was much higher than in the IC group (31.3% vs. 0 percent, P<0.001). HRQL score increased significantly in both groups following treatment and follow-up evaluations (P<0.001). The HRQL score of the IC group at 3 months after therapy was significantly higher than that of the MIC group (88.9 vs. 85.7, P<0.001), showing a larger increment from baseline scores compared to the MIC group (5.4 vs. 2.6, P<0.001).
Conclusion: HRQL in CHD children showed a continuous improvement regardless of IC or MIC intervention. But IC could lead to better HRQL in the early postoperative stage.