AUTHOR=Park Jae Ho , Lim Nam-Kyoo , Park Hyun-Young 

TITLE=Association of leisure-time physical activity and resistance training with risk of incident hypertension: The Ansan and Ansung study of the Korean Genome and Epidemiology Study (KoGES)

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1068852

DOI=10.3389/fcvm.2023.1068852

ISSN=2297-055X

ABSTRACT=Hypertension is the most common risk factor for the incidence of and mortality associated with cardiovascular disease. We aimed to investigate the association between incident hypertension and 4-year leisure-time physical activity (PA) and resistance training (RT) levels. In this community-based Korean cohort, 5,075 participants without hypertension were included. To evaluate cumulative PA, the average PA time (the total time of moderate-intensity leisure-time PA) at baseline, 2-year follow-up, and 4-year follow-up were calculated. Participants were categorized into four groups based on their participation in RT and adherence to PA guidelines (≥150 min/week of PA time) as follows: Low-PA, Low-PA+RT, High-PA, and High-PA+RT. A multivariate Cox proportional hazards regression model was used to assess the 12-year incidence of hypertension according to leisure-time PA levels and RT regularity. During a mean 7.86 ± 4.20-year follow-up, 2,544 participants (1,366 women) were diagnosed with hypertension. Compared with Low-PA, High-PA and High-PA+RT decreased the risk for hypertension by 30% and 39%, respectively. Participation in RT without compliance to PA guidelines did not affect the incidence of hypertension. We further analyzed the additive effect of RT on hypertension in the High-PA group. Although sex-based comparisons indicated that men had a significantly longer training period for RT than women, an additional reduction in the risk for hypertension in relation to the addition of RT was observed only in women (35%). PA may confer protective effects against hypertension, whereas the addition of RT to high levels of PA can further decrease the risk for hypertension in women.