AUTHOR=Chen Xiaomin , Lin Guoli , Dai Caizhi , Xu Kaizu 

TITLE=Effect of estimated plasma volume status and left atrial diameter on prognosis of patients with acute heart failure

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1069864

DOI=10.3389/fcvm.2023.1069864

ISSN=2297-055X

ABSTRACT=Objective
Acute heart failure (AHF) was a common cardiovascular emergency with high mortality and readmission rates. The aim was to investigate the predictive value of estimated plasma volume status (ePVs) and left atrial diameter (LAD) for the prognosis of patients with AHF.
Methods
Clinical profile were collected from 259 patients with AHF at the Affiliated Hospital of Pu-tian University from September 2019 to October 2021.
Results
6 patients were lost to follow-up, and 253 patients were finally enrolled. Cardiogenic death and readmission for heart failure during the follow-up were defined as major cardiovascular events (MACE) group, other patients were defined as Non-MACE group. There were no significant differences in demography and comorbidities between the two groups except age. The differences between the two groups in ePVs, LAD, N-terminal-pro B type natriuretic peptide (Nt-pro-BNP) were statistically significant (P<0.05). Binary logistic regression analysis showed that ePVs (OR=2.061, 95%CI 1.322~3.214, P=0.001), LAD (OR=1.054, 95%CI 1.012~1.098, P=0.011) and Nt-pro-bnp (OR=1.006, 95%CI 1.003~1.010, P=0.036) were predictors of MACE (P< 0.05). Kaplan-Meier analysis showed that the risk of cardiogenic death increased with increasing ePVs. (p<0.05).
Conclusions
ePVs and LADs have some predictive value in assessing cardiogenic death and heart failure readmission in patients with AHF.