AUTHOR=Schaeffer Thibault , Koechlin Luca , Jeger Raban , Leibundgut Gregor , Reuthebuch Oliver 

TITLE=Severe structural valve deterioration after TAVR with ACURATE Neo: report of two cases

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1135496

DOI=10.3389/fcvm.2023.1135496

ISSN=2297-055X

ABSTRACT=Structural valve deterioration (SVD) of transcatheter implanted aortic valve (TAVR) prostheses leading to prosthesis dysfunction is an uncommon but increasingly described complication. Literature is scarce on specific mechanisms and clinical presentation of SVD after TAVR, notably on the self-expanding valve ACURATE Neo. We report on two cases of severe bioprosthetic failure due to leaflet disruption less than five years after ACURATE Neo implantation, which we treated with surgical aortic valve replacement. We further discuss the incidence of SVD after TAVR, the durability of ACURATE NEO, and the modes of failure of biological valve prostheses.