AUTHOR=Valore Luca , Junker Till , Heilmann Eva , Zuern Christine S. , Streif Matthias , Drexler Beatrice , Arranto Christian , Halter Jörg P. , Berger Christoph T. 

TITLE=Case report: mRNA-1273 COVID-19 vaccine-associated myopericarditis: Successful treatment and re-exposure with colchicine

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1135848

DOI=10.3389/fcvm.2023.1135848

ISSN=2297-055X

ABSTRACT=Introduction: Vaccine-induced myopericarditis is a rare complication of mRNA vaccines against SARS-CoV2. Case presentation: We report a case of an acute myopericarditis in a recipient of allogeneic hematopoietic cells following the first dose of the mRNA-1273 vaccine and the successful administration of a second and third dose while on prophylactic treatment with colchicine to successfully complete the vaccination. Conclusions: Treatment and prevention of a mRNA-vaccine induced myopericarditis represent a clinical challenge. Use of colchicine is feasible and safe in order to manage this rare but severe complication and allow re-exposition to vaccine.