AUTHOR=Kwok Cecilia , Nolan Mark 

TITLE=Cardiotoxicity of anti-cancer drugs: cellular mechanisms and clinical implications

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1150569

DOI=10.3389/fcvm.2023.1150569

ISSN=2297-055X

ABSTRACT=Cardio-oncology is an emerging field that seeks to improve quality of life and survival of many survivors of cancer. It is pertinent for clinicians to understand the cellular mechanisms of prescribed therapies, as improved clinician understanding contribute to more accurate communication with patients. Our aim is to review the cellular mechanisms of cardiotoxicity involved in commonly used anti-cancer treatments. We hope to identify gaps in literature and strategies to mitigate the effects of cardiotoxicity that could guide future research endeavours.