AUTHOR=Xie Ying , Yang Jing , Li Kun , Liu Fang , Yi Yi , Zhang Ping TITLE=Case report: A case of hypocalcemic cardiomyopathy with non-reversible cardiac fibrosis JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 10 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1166600 DOI=10.3389/fcvm.2023.1166600 ISSN=2297-055X ABSTRACT=Hypocalcaemic cardiomyopathy (HC) is a rare etiology of heart failure. It was considered highly reversible with a relatively favorable prognosis. This case reports a 52-year-old housewife diagnosed with hypocalcaemic cardiomyopathy, who presented with acute decompensated heart failure and hypocalcaemia symptoms with a history of thyroidectomy. Shortness of breath and edema were relieved after diuresis and prompt electrolyte correction. Left ventricular ejection fraction (LVEF) increased from 27% to 53% and left ventricular end-diastolic dimension (LVEDD) shorted from 58mm to 50mm in echocardiographic re-examinations, while repeat cardiac magnetic resonance imaging revealed evidence of non-reversible cardiac fibrosis after 1-year follow-up. Cardioprotective agents with close follow-up is called for in this entity of patients.