AUTHOR=Cai Sidong , Huang Fangmei , Wang Run , Wu Min , Liu Mingya , Peng Yufen , Cao Gaozhen , Li Yapin , Liu Shuhong , Lu Jiena , Su Mengqi , Wei Yinxia , Yiu Kai-Hang , Chen Cong 

TITLE=Habitual physical activity improves outcomes among patients with myocardial infarction

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1174466

DOI=10.3389/fcvm.2023.1174466

ISSN=2297-055X

ABSTRACT=Purpose: To evaluate the association between habitual physical activity (HPA) and the outcomes of patients with myocardial infarction (MI).
Methods: Patients newly diagnosed with MI were divided into two groups based on whether they engaged in HPA, defined as aerobic activity with a duration of no less than 150 min/wk, before the index admission. The primary outcomes included major adverse cardiovascular events (MACEs), cardiovascular (CV) mortality and cardiac readmission rate 1 year following the index date of admission. A binary logistic regression model was applied to analyse whether HPA was independently associated with 1-year MACEs, 1-year CV mortality and the 1-year cardiac readmission rate.
Results: Among 1266 patients (mean age 63.4 years, 72% male), 571 (45%) engaged in HPA, and 695 (55%) did not engage in HPA before MI. Patients who participated in HPA were independently associated with a lower Killip class upon admission (OR = 0.48: 95% CI, 0.32 - 0.71, p < 0.001) and a lower prevalence of 1-year MACEs (OR = 0.74: 95% CI, 0.56 - 0.98, p = 0.038) and 1-year CV mortality (OR = 0.50: 95% CI, 0.28 - 0.88, p = 0.017) than those who did not participate in HPA. HPA was not associated with cardiac-related readmission (OR = 0.87: 95% CI, 0.64 - 1.17, p = 0.35). 
Conclusions: HPA before MI was independently associated with a lower Killip class upon admission, 1-year MACEs and 1-year CV mortality rate.
Keywords: habitual physical activity, myocardial infarction, major adverse cardiovascular events, cardiovascular mortality