AUTHOR=Kwon Soonil , Lee So-Ryoung , Choi Eue-Keun , Lee Seung-Woo , Jung Jin-Hyung , Han Kyung-Do , Ahn Hyo-Jeong , Oh Seil , Lip Gregory Y. H. 

TITLE=Impact of components of metabolic syndrome on the risk of adverse renal outcomes in patients with atrial fibrillation: a nationwide cohort study

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1208979

DOI=10.3389/fcvm.2023.1208979

ISSN=2297-055X

ABSTRACT=The renal effect of metabolic syndrome components is unclear in patients with atrial fibrillation. This study aimed to investigate the association between metabolic syndrome components and incident end-stage renal disease among patients with atrial fibrillation.Methods: A total of 202,434 atrial fibrillation patients without prevalent end-stage renal disease were identified from the National Health Insurance Service database between 2009 and 2016. We defined the metabolic score range from 0 to 5 points such that a patient received every 1 point if the patient met each component listed in the diagnostic criteria of metabolic syndrome. The population was divided into 6 groups: MS0~MS5 for a metabolic score of 0~5, respectively. Multivariate Cox regression analysis was used to estimate the risks of end-stage renal disease.