AUTHOR=Huang Jing-bin , Lu Chang-chao , Wen Zhao-ke , Yang Jian-rong , Li Jun-jun TITLE=Surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery in China JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 10 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1217148 DOI=10.3389/fcvm.2023.1217148 ISSN=2297-055X ABSTRACT=Introduction: We aimed to investigate surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery.Methods: This was a retrospective study of patients with left-sided infective endocarditis and symptomatic neurological complications before surgery undergoing cardiac surgery between January 2006 and November 2022 at our hospital.Results: 832 patients were divided into group with symptomatic neurological complications before surgery (n=112) and without symptomatic neurological complications before surgery (n=720). There were 48 operative deaths (5.4%).Univariate and multivariate analyses showed that symptomatic neurological complications before surgery is statistically significantly associated with in-hospital mortality following cardiac surgery and prolonged intubation time.Conclusions: Our study showed that symptomatic neurological complications before surgery are associated with increased in-hospital mortality following cardiac surgery and prolonged intubation time.