AUTHOR=Ding Zihao , Du Shihong , Yang Yi , Yu Tong , Hong Xiuqin 

TITLE=Association between triglyceride glucose index and H-type hypertension in postmenopausal women

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1224296

DOI=10.3389/fcvm.2023.1224296

ISSN=2297-055X

ABSTRACT=Background Recent studies have reported better predictive performance of triglyceride glucose (TyG) index for cardiovascular events in women, however, whether this association persists in postmenopausal women is inconclusive. We investigated the association between TyG index and H-type hypertension (HHT) in postmenopausal women. Methods 1301 eligible women with hypertension were included in this crosssectional study. Concomitant homocysteine levels > 10 μmol/L were defined as Htype hypertension. The TyG index was calculated as ln [triglycerides (mg/dL) × fasting glucose (mg/dL)/2]. Multivariable logistic regression models and restricted cubic spline models were used to assess the association between TyG index and Htype hypertension in postmenopausal women, and subgroup analyses were performed for potential confounders. Results Of the 1301 hypertensive patients, 634 (48.7%) participants had H-type hypertension. In each adjusted model, TyG index was significantly associated with the risk of H-type hypertension. each 1-unit increase in TyG index was associated with an increased risk of H-type hypertension in all participants (OR=1.6; 95% CI, 1.3-2.0; P<0.001), and there was a linear relationship between TyG index and H-type hypertension (P for linear trend < 0.001). Conclusion TyG index is positively associated with H-type hypertension in postmenopausal women, suggesting that TyG index may be a promising marker for H-type hypertension. By controlling lipid levels and blood glucose levels, it may help prevent H-type hypertension in postmenopausal women.