AUTHOR=Schmitz Timo , Wein Bastian , Raake Philip , Heier Margit , Peters Annette , Linseisen Jakob , Meisinger Christa TITLE=Do patients with diabetes with new onset acute myocardial infarction present with different symptoms than non-diabetic patients? JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 11 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2024.1324451 DOI=10.3389/fcvm.2024.1324451 ISSN=2297-055X ABSTRACT=The objective of this study was to investigate the differences in presenting symptoms between patients with and without diabetes being diagnosed with an acute myocardial infarction (AMI).Methods: A total of 5,900 patients with a first-time AMI were included into the analysis. All patients aged between 25 to 84 years were recorded by the population-based Myocardial Infarction Registry in Augsburg, Germany, between 2010 and 2017. The presence (yes/no) of 11 AMI typical symptoms during the acute event was assessed within the scope of a face-toface interview. Multivariable adjusted logistic regression models were calculated to analyze the associations between presenting symptoms and diabetes mellitus in AMI patients.Results: Patients with diabetes had significantly less frequent typical pain symptoms, including typical chest pain. Also, other symptoms like sweating, vomiting/nausea, dizziness/vertigo and fear of death/feeling of annihilation occurred significantly more likely in non-diabetic patients.The only exception was the symptom of shortness of breath, which was found significantly