AUTHOR=Bacigalupi Elena , Pizzicannella Jacopo , Rigatelli Gianluca , Scorpiglione Luca , Foglietta Melissa , Rende Greta , Mantini Cesare , Fiore Franco M. , Pelliccia Francesco , Zimarino Marco 

TITLE=Biomechanical factors and atherosclerosis localization: insights and clinical applications

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2024.1392702

DOI=10.3389/fcvm.2024.1392702

ISSN=2297-055X

ABSTRACT=Elena Bacigalupi has nothing to disclose Jacopo Pizzicannella has nothing to disclose Luca Scorpiglione has nothing to disclose Gianluca Rigatelli has nothing to disclose Cesare Mantini has nothing to disclose Melissa Foglietta has nothing to disclose Greta Rende has nothing to disclose Franco M Fiore has nothing to disclose Francesco Pelliccia has nothing to disclose Marco Zimarino has nothing to disclose The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.• Biomechanical factors contribute to valuable prognostic information beyond anatomical and physiological plaque characteristics in the localization and evolution of coronary atherosclerosis.• Computational fluid dynamics offers clinical applications in the assessment of plaque vulnerability, coronary lesion severity, stent-vessel interactions, and coronary bifurcation complexities.