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REVIEW article

Front. Cardiovasc. Med.
Sec. Structural Interventional Cardiology
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1427189
This article is part of the Research Topic Advance in the Etiology, Imaging Diagnosis and Interventional Treatment of Cardiogenic Stroke View all articles

Device-related thrombus after percutaneous left atrial appendage closure: incidence, predictors, clinical impacts, and managements

Provisionally accepted
Zhitong Liu Zhitong Liu Ziyong Hao Ziyong Hao Lisheng Jiang Lisheng Jiang Ben He Ben He *
  • Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China

The final, formatted version of the article will be published soon.

    Left atrial appendage closure (LAAC) is an important alternative to anticoagulation therapy for patients with nonvalvular atrial fibrillation, and has been increasingly performed in the recent years. However, the device-related thrombosis (DRT), an infrequent but dreadful complication associated with an increased risk of ischemic events has not been fully recognized. Currently, there is no consensus on the anticoagulation strategy after LAAC, and recent clinical studies have provided novel options for postprocedural antithrombotic regimens. In this review, we summarized the incidence, predictors, diagnosis, and clinical impacts of DRT, and evaluate the current evidence of postprocedural antithrombotic strategies.

    Keywords: Left atrial appendage closure, device-related thrombosis, predictors, clinical impacts, antithrombotic strategy

    Received: 03 May 2024; Accepted: 22 Jul 2024.

    Copyright: © 2024 Liu, Hao, Jiang and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ben He, Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.