AUTHOR=Albulushi Arif , Al Harthi Faisal , Aly Gamal , Al-Wahshi Yahya , El-Deeb Mohammed H. 

TITLE=Comparative hemodynamic responses to upright and recumbent cycling in patients with exercise intolerance

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 11 - 2024

YEAR=2025

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2024.1431787

DOI=10.3389/fcvm.2024.1431787

ISSN=2297-055X

ABSTRACT=IntroductionUnderstanding the influence of body position on cardiovascular responses during exercise is crucial for precise diagnostic and therapeutic strategies, particularly in patients with exercise intolerance.AimThis study aims to compare the hemodynamic responses to exercise in upright and recumbent cycling positions in patients with exercise intolerance.MethodsA cross-over study design was employed, enrolling 21 patients for right heart catheterization during exercise in both upright and recumbent positions. Hemodynamic variables were measured at rest and across various exercise intensities.ResultsSignificant differences were observed in right atrial pressure (RAP), mean pulmonary artery pressure (mPAP), and pulmonary artery wedge pressure (PAWP) between upright and recumbent positions. Upright exercise revealed lower values of RAP, mPAP, and PAWP, indicating distinct hemodynamic profiles.ConclusionBody position significantly affects cardiovascular dynamics during exercise, providing valuable insights for diagnosing and managing exercise intolerance.