AUTHOR=Labaste François , Lavie-Badie Yoan , Bouchau Robin , Boyère Lucie , Sanchez-Verlaan Pascale , Gonzalez Hélène , Marcheix Bertrand , Botea Roxana , Vardon-Bounes Fanny , Minville Vincent 

TITLE=Predictors of low cardiac output syndrome after combined mitral and tricuspid valve surgery

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2024.1452820

DOI=10.3389/fcvm.2024.1452820

ISSN=2297-055X

ABSTRACT=Introduction: Low cardiac output syndrome (LCOS) is a common complication in cardiac surgery, and we evaluated the incidence of its early occurrence after mitral and tricuspid combined cardiac surgery and its associated risk factors. 
Material and method: Retrospective, single institution study. We included 88 consecutive adult patients with severe mitral insufficiency scheduled for elective mitral and tricuspid valve replacement surgery between January 2015 and November 2018. The primary endpoint was the occurrence of LCOS, defined as the need for inotropic support or circulatory assistance after surgery. The secondary endpoint was mortality at 30 days. 
Results: LCOS occurs in 26 patients (29.5%) and its associated risk factors that appeared in the multivariate analysis were chronic kidney failure (adjusted odd ratio (OR) 3.1 ; 95% [CI] 1.0 – 9.9, p=0.05), preoperative left ventricular heart failure (OR 5.3 ; 95% [CI] 1.3 – 10.9, p=0.002), preoperative right ventricular heart failure (OR 3.6 ; 95% [CI] 1.1 – 11.5, p=0.02), mitral valve replacement (OR 3.9 ; 95% [CI] 1.2 – 12.6, p=0.03). LCOS affected the survival of patients (HR = 5.5 ; 95% [CI] 1.1 – 27.7 p = 0.04).
Conclusion: LCOS is a frequent complication after mitral and tricuspid combined surgery and is associated with a poor prognostic.