AUTHOR=Idu Muhammad , Lim Chiw Yeh , Chua Kim Chai TITLE=Case Report: Late presentation of post-coronary artery bypass surgery pericardial effusion heralding mediastinitis with tracheocutaneous fistula JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1483395 DOI=10.3389/fcvm.2025.1483395 ISSN=2297-055X ABSTRACT=Post-coronary artery bypass surgery pericardial effusions are typically self-limiting but may rarely be significant, causing pericardial tamponade. We describe a case of late post-operative pericardial effusion that required pericardiocentesis and subsequent readmission for mediastinitis with the added complication of a tracheocutaneous fistula. Our case report is the first reported instance of pericardial tamponade heralding the onset of mediastinitis. It also describes the rare complication of tracheocutaneous fistula associated with mediastinitis.