AUTHOR=Li Liu-Cheng , Zhang Su , Sun Jia-Bin , Xu Yao-Yao , Mao Kai-Li 

TITLE=Case Report: Practice of whole-course pharmaceutical care: a case in hypertrophic cardiomyopathy and a review of the pharmacist’s role

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1512784

DOI=10.3389/fcvm.2025.1512784

ISSN=2297-055X

ABSTRACT=Clinical pharmacists supported clinicians in medication planning and health education for a male patient diagnosed with hypertrophic cardiomyopathy (HCM). Therapeutically, diltiazem was replaced with metoprolol to further alleviate symptoms. Whole-blood exon sequencing revealed a pathogenic mutation in the beta-myosin heavy chain gene (MYH7, OMIM #160760), consistent with dominant inheritance. Furthermore, low-intensity exercise and screening of the patient’s children were recommended. In addition, we provided an overview of current therapeutic approaches, emphasizing potential novel agents and non-pharmaceutical interventions for HCM management. This is the first case report to highlight not only updates in HCM treatment but also the pharmacist’s role in long-term HCM management.