AUTHOR=Zhao Teng-Yue , Wang Bing-Jie , Liu Chu , Liu Jiang , Bu Ji-Qiang , Liu Yu , Zhao Shu-Guang , Zhang Wen-Li , Chen Zi-Ying , Wu Yu-Ming TITLE=Comparing 3-month and 1-year patency rates of no-touch great saphenous vein and pedicled left internal mammary artery in off-pump coronary artery bypass grafting: a prospective non-inferiority study JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1547482 DOI=10.3389/fcvm.2025.1547482 ISSN=2297-055X ABSTRACT=ObjectiveIn this study, we compared the 3- and 12-month patency rates of great saphenous vein (GSV) grafts harvested using the no-touch technique and pedicled left internal mammary artery (LIMA) in off-pump coronary artery bypass grafting (OPCABG). We also evaluated the short-term efficacy of the grafts harvested using the no-touch technique.MethodsA non-inferiority study was conducted between June 2019 and August 2022, involving 106 patients who underwent OPCABG using the “no-touch” technique to harvest grafts from the LIMA and GSV. We aimed to assess and compare the patency rates of the pedicled LIMA graft and the no-touch GSV graft at both the 3- and 12-month postoperative intervals. Additionally, we sought to evaluate the advantages of employing the no-touch GSV graft in the context of OPCABG.ResultsThere was no statistically significant difference in patency between the no-touch GSV graft and the LIMA at 3 and 12 months post-OPCABG (P < 0.001).ConclusionThe no-touch technique can provide graft patency comparability with the LIMA; therefore, in addition to the internal mammary artery, the no-touch GSV is recommended as a graft alternative.