AUTHOR=Kokhanovskyi Ivan , Castillo-Passi Carlos , Crabb Michael G. , Ganter Carl , Littlewood Simon J. , Kunze Karl P. , Karampinos Dimitrios C. , Makowski Marcus R. , Rueckert Daniel , Prieto Claudia , Botnar René M. 

TITLE=High-resolution 3D whole-heart bright- and black-blood imaging with co-registered T2 mapping at 0.55 T

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1572318

DOI=10.3389/fcvm.2025.1572318

ISSN=2297-055X

ABSTRACT=IntroductionConventional CMR exams for assessment of cardiac anatomy and tissue characterization require multiple sequential 2D acquisitions under breath-hold in different orientations, in addition to being limited to 1.5 T and 3 T.MethodsIn this study, we sought to develop a novel 3D motion-compensated free-breathing sequence for comprehensive high-resolution whole-heart assessment of cardiovascular anatomy via simultaneous bright- and black-blood imaging and co-registered T2 myocardial tissue quantification in a one-click scan at 0.55 T.ResultsGood agreement with a spin-echo reference sequence was found in the phantom for T2 mapping. In-vivo, the proposed research sequence was evaluated in 10 healthy subjects, providing great delineation of cardiac and vascular structures, good visibility of coronary arteries and accurate T2 parametric mapping in a clinically feasible time of less than 9 min.