AUTHOR=Dávid Kamilla Luca , Polgár Balázs , Bógyi Péter , Bári Zsolt , Marczell István , Bogdan Manuella , Gulyás Zalán , Turáni Mirjam Franciska , Papp Judit , Zsigmond Előd János , Tóth-Zsámboki Emese , Duray Gábor Zoltán TITLE=Acute and long-term procedural outcomes, arrhythmia recurrence and mortality after supraventricular arrhythmia ablation: a comparative study of fluoroscopy and zero-fluoroscopy guided techniques JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1582753 DOI=10.3389/fcvm.2025.1582753 ISSN=2297-055X ABSTRACT=Background and aimsZero-fluoroscopy (ZF) catheter ablation eliminates radiation exposure via use of 3-dimensional electroanatomical mapping. We aimed to assess safety and efficacy of ZF catheter ablation in the treatment of supraventricular tachycardias (SVTs), examine learning-curve characteristics and to evaluate long-term results and mortality.MethodsWe analysed clinical characteristics, procedural and follow-up data of 605 consecutive patients undergoing catheter ablation for SVT (atrioventricular nodal re-entry tachycardia, n = 297; atrial flutter, n = 241 and accessory pathway mediated tachycardia, n = 67) between June 2017 and September 2021. Procedures were either guided by conventional fluoroscopy (F, n = 223) or by EnSite Precision mapping system (ZF, n = 382) based on decision of the operating physician.ResultsAcute procedural success rate exceeded 98% across all arrhythmia groups for both ZF and F techniques (ZF: 99%, F: 100%, p = NS). 63% of patients underwent ZF procedures. Complication rate was low (0.66%), occurring only in the F group. Conversion rate to fluoroscopy was 7.8%. ZF procedures took an average of 5.1 min longer (ZF: 64.5 ± 24.3 min vs. F: 59.4 ± 29 min, p < 0.05), however ZF procedure times were reduced over time. At 3.2 years, total mortality was 7% with no significant difference between ZF and F. Deaths were not related to the procedures. Atrial flutter showed significantly higher recurrence in ZF compared to F (83% vs. 94%, p < 0.005).ConclusionCatheter ablation of SVTs using zero-fluoroscopy approach have similar acute success, complication and mortality rate as conventional fluoroscopic interventions. However, we detected significantly higher long-term arrhythmia recurrence after ZF ablation of atrial flutter, meriting further investigation.