AUTHOR=Lai Yurui , Fang Chenli , Jiang Yuang , Yang Chengying , Zhou Qiao , Cai Yihua , Wei Yan , Fan Xinrong 

TITLE=Novel opportunity of treatment for psycho-cardiologic disease by gut microbiome

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1604962

DOI=10.3389/fcvm.2025.1604962

ISSN=2297-055X

ABSTRACT=Cardiovascular disease (CVD) patients combined with depression, anxiety, and other psychiatric disorders are becoming a common occurrence. There are many comorbid mechanisms, and CVD patients with psychiatric disorders have poor prognosis. Several studies have shown that dysbiosis and metabolite alterations in the gut were major risk factors for CVD and psychosomatic disorders. This review aims to summarize the mechanisms of gut microbiota and its metabolites in psycho-cardiologic disease, and the therapeutic effects of gut microbiota interventions. It is very useful to propose a new direction for the treatment of psycho-cardiologic disease.