AUTHOR=Chen Yingjie , Yu Wei , Liu Min , Liu Qunxiang , Qin Wei , Zhu Ziyang , Chen Shi , Li Chenghong , Li Fajiu 

TITLE=Concurrent hemorrhage and thrombosis: a case report of hemoptysis from pulmonary vein stenosis with left ventricular thrombus

JOURNAL=Frontiers in Cardiovascular Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2025.1666077

DOI=10.3389/fcvm.2025.1666077

ISSN=2297-055X

ABSTRACT=We report a rare case of concurrent pulmonary vein stenosis (PVS) and left ventricular thrombus (LVT) in a 46-year-old male with dilated cardiomyopathy and prior radiofrequency catheter ablation for atrial fibrillation, who presented with hemoptysis and dyspnea. Imaging confirmed left pulmonary vein occlusion and LVT, creating a therapeutic conflict between bleeding control and anticoagulation. We implemented a staged strategy: urgent balloon angioplasty and large-diameter bare-metal stent implantation to improve PVS hemodynamics and halt hemoptysis; subsequently, rivaroxaban and clopidogrel were initiated for LVT. At 6-month follow-up, symptoms resolved with complete LVT absorption, though LIPV developed in-stent re-occlusion. This demonstrated that prioritizing PVS intervention before anticoagulation effectively balances hemorrhage and thrombosis risks in this complex scenario.