AUTHOR=Durston Antony J. 

TITLE=Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning

JOURNAL=Frontiers in Cell and Developmental Biology

VOLUME=Volume 7 - 2019

YEAR=2019

URL=https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2019.00257

DOI=10.3389/fcell.2019.00257

ISSN=2296-634X

ABSTRACT=Abstract
The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity. Here, I focus on the two current competing models based on this premise. Common features and points of dissent are examined and a common model is distilled from what remains. This is an attempt to make sense of the literature.