AUTHOR=Younes Salma , Al-Sulaiti Asma , Nasser Elham Abdulwahab Ahmed , Najjar Hoda , Kamareddine Layla 

TITLE=Drosophila as a Model Organism in Host–Pathogen Interaction Studies

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=Volume 10 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2020.00214

DOI=10.3389/fcimb.2020.00214

ISSN=2235-2988

ABSTRACT=Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host-pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in Drosophila serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.