AUTHOR=Freire-Paspuel Byron , Vega-MariƱo Patricio , Velez Alberto , Castillo Paulina , Gomez-Santos Eliana Elizabeth , Cruz Marilyn , Garcia-Bereguiain Miguel Angel TITLE=Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=Volume 10 - 2020 YEAR=2020 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2020.00356 DOI=10.3389/fcimb.2020.00356 ISSN=2235-2988 ABSTRACT=CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton tipped plastic swabs are massively produced worldwide and would prevent swabs supplies shortage during current high SARS-CoV2 testing demands, particularly on developing countries.