AUTHOR=Wang Xuelin , Hou Liming , Cui Meng , Liu Junnan , Wang Mengzhou , Xie Jianwu TITLE=The traditional Chinese medicine and non-small cell lung cancer: from a gut microbiome perspective JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=Volume 13 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2023.1151557 DOI=10.3389/fcimb.2023.1151557 ISSN=2235-2988 ABSTRACT=Non-small cell lung cancer (NSCLC) is one of the major diseases affecting human health at present, and intestinal flora is the focus of current research. There is a correlation between intestinal flora imbalance and lung cancer, but the specific mechanism is not clear. Based on the “lung and large intestine being interior-exteriorly related” and the “lung-intestinal axis”theory. This paper, through the theoretical comparison of Chinese and western medicine, summarizes and analyzes the regulation of intestinal flora of NSCLC by active ingredients of traditional Chinese medicine and Chinese herbal compounds and their intervention effects, which is conducive to providing new strategies and ideas for clinical prevention and treatment of NSCLC.