AUTHOR=Chávez-Vélez Erik , Álvarez-Nava Francisco , Torres-Vinueza Alisson , Balarezo-Díaz Thalía , Pilataxi Kathya , Acosta-López Camila , Peña Ivonne Z. , Narváez Katherin 

TITLE=Single nucleotide variants in the CCL2, OAS1 and DPP9 genes and their association with the severity of COVID-19 in an Ecuadorian population

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=Volume 14 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1322882

DOI=10.3389/fcimb.2024.1322882

ISSN=2235-2988

ABSTRACT=COVID-19 has a broad clinical spectrum, ranging from asymptomatic-mild form to severe phenotype. The severity of COVID-19 is a complex trait influenced by various genetic and environmental factors. Ethnic differences have been observed in relation to COVID-19 severity during the pandemic. It is currently unknown whether genetic variations may contribute to the increased risk of severity observed in Latin-American individuals The aim of this study is to investigate the potential correlation between gene variants at CCL2, OAS1, and DPP9 genes and the severity of COVID-19 in a population from Quito, Ecuador.